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Doctor Points to Studies Suggesting That Acupuncture As Effective at Treating Moderate Depression As Antidepressants

September 10, 2012

acupuncture.jpegFor those who suffer from depression, bipolar disorder, or other imbalances of the brain, one doctor proposes using acupuncture as an alternative to antidepressant medication. Pregnant women who choose this approach may have the added benefit of reducing the risk of their children being born with birth defects.

Dr. Patrick Massey argues that recent research has found that while antidepressants can help those with severe depression, they have less obvious benefits for those with milder depression. In clinical tests, antidepressants were no more effective for people with milder depression than sugar pills functioning as placebos. Dr. Massey thinks that this is due to many factors contributing to depression besides brain chemistry.

Dr. Massey points to a recent study in the Canadian Journal of Psychiatry, which looked at a compilation of studies that examined the effectiveness of acupuncture at relieving moderate depression for people across a broad age span. The study ultimately found that acupuncture was at least as effective as antidepressants, and when coupled with antidepressants, might reduce some of the side effects. Dr. Massey cautions that the weight of medical research on the subject is not conclusive, but notes that at the very least, it shows that acupuncture is an effective therapy for those with depression. In addition, exercise and meditation have also been shown to be effective alternatives.

While the studies on acupuncture as an alternative are promising, those with depression should do their research before making the choice to go with acupuncture over antidepressants. That includes working with their physician to get an accurate assessment of their mental health so that they can make an informed choice. However, if you are pregnant with moderate depression, and you opt to use acupuncture instead of antidepressants, you might have the benefit of lowering your child's risk of being born with a birth defect. That is because certain antidepressants have been linked to causing a variety of birth defects, especially if women take them during the first trimester. Antidepressants like Depakote have been classified as Pregnancy Category D drugs - evidence of harm to human fetuses - by the Food and Drug Administration as a result.

If your child has a birth defect that you believe could be due to your taking antidepressants while pregnant, you might consider filing a product liability lawsuit against the manufacturer and/or a medical malpractice suit against the physician who prescribed you the medication. For the product liability lawsuit, you would make the argument that the manufacturer had a duty to consumers to create as safe a drug as possible, and the manufacturer breached that duty by designing a drug that was unreasonably dangerous. The breach caused your injury (through exposure to the antidepressant's harmful effects) and the damage was your child's birth defect. For the medical malpractice lawsuit, you would argue that your physician had a duty to inform you, the patient, of all of the potential harms of your course of treatment. Your physician breached this duty by failing to inform you of all of the harmful side effects of your antidepressants, even though he or she knew that you were pregnant. As a result, you would argue that you were injured through exposure, and the damage was your child's birth defect.

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Valproate, Antiepileptic Drugs Linked to Lower IQ

May 4, 2011

scoldedbw.jpgA study published in the New England Journal of Medicine found evidence of lower cognitive functioning in young children who were exposed to antiepileptic drugs while in the womb. The study was entitled "Cognitive Function at 3 Years of Age After Fetal Exposure to Anti-Epileptic Drugs."

Previous studies on animals had found that fetuses exposed to antiepileptic drugs could develop cognitive abnormalities; however, the effects of these drugs on human fetuses were still unknown. The study observed women between the years 1999 to 2004 who were taking the anti-epileptic drugs carbamazepine, lamotrigine, phenytoin (Dilantin) or valproate (Depakote). Researchers then compared the cognitive functioning of 309 children by the time they were 3 years of age.

The study found that children who had been exposed to valproate in the womb had considerably lower IQ scores compared to those exposed to other antiepileptic drugs. Children who had been exposed to valproate (Depakote) in utero scored an average of 9 points lower IQ than children who were exposed to lamotrigine; 7 points lower than those exposed to phenytoin (Dilantin), and 6 points lower than exposed to carbamazepine. The study also found that larger doses of valproate, were correlated with lower IQ scores. In sum, the study found a significant link between exposure to valproate (Depakote) in the womb and reduced cognitive function by 3 years of age.

The FDA has classified many antiepileptic drugs as pregnancy category D drugs, which means that there is positive evidence of risk to human fetuses. The FDA strongly recommends that pregnant women not use medications in category D unless the benefits of the drug outweigh the risk to the fetus. Many antiepileptic drugs are in pregnancy category D, including Depakote, Dilantin, and Topamax.

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Dilantin Use Linked to Increased Birth Defect Risk

April 13, 2011

DSCF1848.jpgDilantin (phenytoin), one of the most popular antiepileptic drugs, can cause an increased risk of major birth defects. Dilantin was approved by the Food & Drug Administration (FDA) in 1953 and is manufactured by Pfizer, Inc. Recently, warning signs about its birth defect risk have emerged. In 2008, the FDA added Dilantin to its "Potential Signs of Serious Risks" list, which meant that there was a possible safety risk with using the drug that needed to be investigated. Also, a recent study published in the New England Journal of Medicine, called "The Teratogenicity of Anticonvulsant Drugs," found that women who used Dilantin during pregnancy had a higher risk of delivering babies with serious birth defects.

Some of the birth defects associated with Dilantin include: cleft lip and cleft palate, mental retardation, growth retardation, neural tube defects, heart defects and Fetal Hydantoin Syndrome. Cleft palate is a split in the roof of the mouth which can lead to other complications such as hearing loss, ear infections and delayed speech development; requiring reconstructive surgery to treat. Fetal Hydantoin Syndrome is a condition that includes several types of birth defects such as cleft lip or cleft palate, underdevelopment, mental retardation, heart defects and limb defects.

Phenytoin, Dilantin's main ingredient, is now known as a teratogen (a substance that causes birth defects). Phenytoin may interfere with the body's ability absorb folic acid; which is necessary to develop red blood cells. The FDA has classified Dilantin as pregnancy category D, which means there is positive evidence in studies on humans that the drug can cause major birth defects.

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